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Acta Paediatr. 2013 Mar;102(3):300-7. doi: 10.1111/apa.12091. Epub 2012 Dec 11.

Follow-up study of 2-year-olds born at very low gestational age in Estonia.

Author information

1
Department of Paediatrics, University of Tartu, Tartu, Estonia. liis.toome@lastehaigla.ee

Abstract

AIM:

To study very low gestational age (VLGA, <32 weeks) infants at 2 years of age and to identify the predictors of adverse outcomes.

METHODS:

A population-based cohort of 155 surviving VLGA infants born in Estonia in 2007 was followed up and compared with a matched full-term (FT) control group. A logistic regression model was used to test associations between risk factors and adverse outcomes.

RESULTS:

No impairment was found in 60% of the VLGA infants. Neurodevelopmental impairment was noted in 12% of VLGA infants, with 8% of the infants affected by cerebral palsy without independent walking, 5% with cognitive delay, 10% with language delay and 1% with hearing impairment. The differences between preterm and FT infants in terms of the mean Cognitive, Language, and Motor Composite Scores assessed using the Bayley-III scales were in excess of 0.5 SD. Somatic growth delay was a significant problem among preterm infants. The existence of severe neonatal cerebral lesions was the most significant predictor of adverse outcomes.

CONCLUSION:

In all domains studied, adverse conditions were more prevalent among VLGA infants than among the FT control group. Efforts to reduce neonatal morbidity in preterm infants should be a key priority for health care in Estonia.

PMID:
23176138
DOI:
10.1111/apa.12091
[Indexed for MEDLINE]

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