Format

Send to

Choose Destination
See comment in PubMed Commons below
BMC Biol. 2012 Nov 21;10:92. doi: 10.1186/1741-7007-10-92.

Logic modeling and the ridiculome under the rug.

Author information

1
Center for Cell Analysis and Modeling, University of Connecticut Health Center, Cell and Genome Sciences Building, 400 Farmington Ave, Farmington, CT 06030-6406, USA.

Abstract

Logic-derived modeling has been used to map biological networks and to study arbitrary functional interactions, and fine-grained kinetic modeling can accurately predict the detailed behavior of well-characterized molecular systems; at present, however, neither approach comes close to unraveling the full complexity of a cell. The current data revolution offers significant promises and challenges to both approaches - and could bring them together as it has spurred the development of new methods and tools that may help to bridge the many gaps between data, models, and mechanistic understanding.

PMID:
23171629
PMCID:
PMC3503555
DOI:
10.1186/1741-7007-10-92
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for BioMed Central Icon for PubMed Central
    Loading ...
    Support Center