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Dermatitis. 2012 Nov-Dec;23(6):275-80. doi: 10.1097/DER.0b013e318273a3e0.

Allergic contact dermatitis in children with and without atopic dermatitis.

Author information

1
Section of Dermatology and Venereology, Department of Medicine, University of Verona, Verona, Italy. donatella.schena@ospedaleuniverona.it

Abstract

BACKGROUND:

Prevalence and causes of allergic contact dermatitis (ACD) in children vary with time and geographical area.

OBJECTIVE:

This study aimed to determine the relevant allergens causing ACD in children and the relation between ACD and atopic dermatitis (AD).

METHODS:

A cohort study on 349 children (0-15 years old) patch tested over a 7-year period was conducted.

RESULTS:

Patch test results were positive for at least 1 allergen in 69.3% of patients and were relevant in 69.8%. The highest sensitization rate (76.7%) was observed in children who are 0 to 5 years old (n = 86, 64% females), followed by the group of 6- to 10-year olds (70%, n = 157, 47.8% females), whereas 62.3% of 11- to 15-year-old children (n = 106, 59.4%) were sensitized. The most frequent allergens were nickel (16.3%), cobalt (6.9%), Kathon CG (5.4%), potassium dichromate (5.1%), fragrance mix (4.3%), and neomycin (4.3%). Body areas mostly affected were upper limbs and hands (31%). Approximately one third of children also had AD. Allergic contact dermatitis was more widespread in children with AD. Patch tests resulted positive in 55.3% (50% relevant) of AD compared with 76.9% (77.5% relevant) of the children without AD. Sensitizers were similar to children without AD.

CONCLUSIONS:

Very young children showed a high rate of relevant positive patch test reactions to common haptens. Allergic contact dermatitis may easily coexist with AD.

PMID:
23169209
DOI:
10.1097/DER.0b013e318273a3e0
[Indexed for MEDLINE]
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