Format

Send to

Choose Destination
Cytokine Growth Factor Rev. 2013 Apr;24(2):105-13. doi: 10.1016/j.cytogfr.2012.10.002. Epub 2012 Nov 16.

Chemokines shape the immune responses to tuberculosis.

Author information

1
Division of Infectious Diseases, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15224, USA.

Abstract

Mycobacterium tuberculosis (Mtb) is the intracellular pathogen that causes the disease, tuberculosis. Chemokines and chemokine receptors are key regulators in immune cell recruitment to sites of infection and inflammation. This review highlights our recent advances in understanding the role of chemokines and chemokine receptors in cellular recruitment of immune cells to the lung, role in granuloma formation and host defense against Mtb infection.

PMID:
23168132
PMCID:
PMC3582802
DOI:
10.1016/j.cytogfr.2012.10.002
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center