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Nanoscale. 2013 Feb 21;5(4):1273-83. doi: 10.1039/c2nr32600k.

Intelligent, self-powered, drug delivery systems.

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Department of Chemistry, Pennsylvania State University, University Park, PA 16802, USA.


Self-propelled nano/micromotors and pumps are considered to be next generation drug delivery systems since the carriers can either propel themselves ("motor"-based drug delivery) or be delivered ("pump"-based drug delivery) to the target in response to specific biomarkers. Recently, there has been significant advancement towards developing nano/microtransporters into proof-of-concept tools for biomedical applications. This review encompasses the progress made to date on the design of synthetic nano/micromotors and pumps with respect to transportation and delivery of cargo at specific locations. Looking ahead, it is possible to imagine a day when intelligent machines navigate through the human body and perform challenging tasks.

[Indexed for MEDLINE]

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