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Toxicol Lett. 2013 Jan 10;216(1):47-53. doi: 10.1016/j.toxlet.2012.11.007. Epub 2012 Nov 16.

Early life exposure to air pollution: how bad is it?

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1
Department of Pediatrics, The Ohio State University, Columbus, OH 43215, USA.

Abstract

Increasing concentrations of air pollution have been shown to contribute to an enormity of adverse health outcomes worldwide, which have been observed in clinical, epidemiological, and animal studies as well as in vitro investigations. Recently, studies have shown that air pollution can affect the developing fetus via maternal exposure, resulting in preterm birth, low birth weight, growth restriction, and potentially adverse cardiovascular and respiratory outcomes. This review will provide a summary of the harmful effects of air pollution exposure on the developing fetus and infant, and suggest potential mechanisms to limit the exposure of pregnant mothers and infants to air pollution.

PMID:
23164674
PMCID:
PMC3527658
DOI:
10.1016/j.toxlet.2012.11.007
[Indexed for MEDLINE]
Free PMC Article
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