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Oncoimmunology. 2012 Sep 1;1(6):982-983.

Radiochemotherapy fosters a favorable pattern of inflammatory cells in head and neck tumors.

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1
Department of Radiation Oncology; University Hospitals, Friedrich-Alexander-University of Erlangen-Nürnberg; Erlangen, Germany.

Abstract

The immune milieu in malignant tumors can influence the prognosis of patients. However, little is known about the effect the antitumoral therapy has on the inflammatory infiltrate. In head and neck squamous cell carcinoma we found evidence that a neoadjuvant radiochemotherapy could modulate the composition of the intratumoral inflammation into an anti-tumoral pattern.

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