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J Clin Invest. 2012 Dec;122(12):4323-4. doi: 10.1172/JCI66746. Epub 2012 Dec 3.

Better tools for assessing osteoporosis.

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1
Endocrine Research Unit, College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA

Abstract

Some 30 years ago, we applied the newly described method of dual photon absorptiometry (DPA) to demonstrate that osteoporotic women with vertebral fractures had lost substantially more bone from the vertebrae than controls. This opened a whole new field of research into the determinants of bone loss and fractures in the axial skeleton and set the stage for subsequent development of dual-energy x-ray absorptiometry (DXA) and quantitative computed tomography (QCT), which are now the standard methods for assessing osteoporosis severity and treatment efficacy.

PMID:
23154276
PMCID:
PMC3533568
DOI:
10.1172/JCI66746
[Indexed for MEDLINE]
Free PMC Article
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