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Cancer Cell. 2012 Nov 13;22(5):565-6. doi: 10.1016/j.ccr.2012.10.014.

PGAMgnam style: a glycolytic switch controls biosynthesis.

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1
Cancer Research UK, The Beatson Institute for Cancer Research, Switchback Road, Glasgow G61 1BD, UK.

Abstract

Therapeutic strategies that target glycolysis and biosynthetic pathways in cancer cells are currently the main focus of research in the field of cancer metabolism. In this issue of Cancer Cell, Hitosugi and colleagues show that targeting PGAM1 could be a way of "killing two birds with one stone".

PMID:
23153529
DOI:
10.1016/j.ccr.2012.10.014
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