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Clin Exp Hypertens. 2013;35(6):412-7. doi: 10.3109/10641963.2012.739236. Epub 2012 Nov 13.

Prevalence and clinical profile of resistant hypertension among treated hypertensive subjects.

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Hypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires , Buenos Aires , Argentina.


We assessed prevalence and clinical characteristics of resistant hypertension (RH) and prevalence of false RH (white-coat effect [WCE] by home blood pressure [BP] monitoring), among a population of 302 treated hypertensive patients, mean age 66.6 (± 13.8), 67.5% women. Resistant hypertension was defined according to the American Heart Association criteria. Prevalence of RH was 10%, and the following five variables were independently associated with it: body mass index, diabetes, isolated systolic hypertension, orthostatic hypotension, and use of beta-blockers. Prevalence of WCE among subjects with office-RH was 27.6%. Our study identified easily measurable parameters related to RH. Standing BP should be systematically measured in individuals with RH.

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