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J Cell Biol. 2012 Nov 12;199(4):577-81. doi: 10.1083/jcb.201209118.

New frontiers in human cell biology and medicine: can pluripotent stem cells deliver?

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1
Department of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, CA 92093, USA. lgoldstein@ucsd.edu

Abstract

Human pluripotent stem cells provide enormous opportunities to treat disease using cell therapy. But human stem cells can also drive biomedical and cell biological discoveries in a human model system, which can be directly linked to understanding disease or developing new therapies. Finally, rigorous scientific studies of these cells can and should inform the many science and medical policy issues that confront the translation of these technologies to medicine. In this paper, I discuss these issues using amyotrophic lateral sclerosis as an example.

PMID:
23148231
PMCID:
PMC3494862
DOI:
10.1083/jcb.201209118
[Indexed for MEDLINE]
Free PMC Article
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