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Nat Rev Microbiol. 2012 Dec;10(12):869-76. doi: 10.1038/nrmicro2900. Epub 2012 Nov 13.

Rethinking vector immunology: the role of environmental temperature in shaping resistance.

Author information

1
Merkle Laboratory, Center for Infectious Disease Dynamics, Department of Entomology, Pennsylvania State University, Orchard Road, University Park, State College, Pennsylvania 16802, USA. ccm15@psu.edu

Abstract

Recent ecological research has revealed that environmental factors can strongly affect insect immunity and influence the outcome of host-parasite interactions. To date, however, most studies examining immune function in mosquitoes have ignored environmental variability. We argue that one such environmental variable, temperature, influences both vector immunity and the parasite itself. As temperatures in the field can vary greatly from the ambient temperature in the laboratory, it will be essential to take temperature into account when studying vector immunology.

PMID:
23147703
PMCID:
PMC4142813
DOI:
10.1038/nrmicro2900
[Indexed for MEDLINE]
Free PMC Article

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