Format

Send to

Choose Destination
See comment in PubMed Commons below
Mayo Clin Proc. 2012 Dec;87(12):1153-61. doi: 10.1016/j.mayocp.2012.07.022. Epub 2012 Nov 9.

Comparison of mastoscopic and conventional axillary lymph node dissection in breast cancer: long-term results from a randomized, multicenter trial.

Author information

1
Fuxing Hospital, Capital Medical University, Beijing, China. luochengyu@163.com

Abstract

OBJECTIVE:

To compare the long-term results of mastoscopic axillary lymph node dissection (MALND) and conventional axillary lymph node dissection (CALND).

PATIENTS AND METHODS:

From January 1, 2003, through December 31, 2005, a group of 1027 consecutive patients with operable breast cancer were randomly assigned to 1 of 2 study groups: MALND and CALND. The median follow-up was 63 months. The primary end points of the study were operative outcomes, complication reduction, function conservation, and cosmetics. The secondary end points were disease-free and overall survival.

RESULTS:

The mean operative blood loss in the MALND group was less than in the CALND group (P<.001). The patients who underwent MALND had less axillary pain, numbness or paresthesias, and arm swelling (P<.001). The aesthetic appearance of the axilla in the MALND group was much better than that in the CALND group (P=.001 at 6 months and P=.002 at 24 months). A significant difference was found between the 2 groups in distant metastasis (P=.04). The disease-free survival rate was 64.5% in the MALND group and 60.8% in the CALND group (P=.88). The overall survival rate was 81.7% in the MALND group and 78.6% in the CALND group (P=.95).

CONCLUSION:

Compared with CALND, MALND has advantages in operative outcomes, complication reduction, function conservation, and cosmetics.

PMID:
23146657
PMCID:
PMC3541933
DOI:
10.1016/j.mayocp.2012.07.022
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Support Center