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Psychiatry Res. 2013 Jan 30;211(1):85-7. doi: 10.1016/j.pscychresns.2012.06.009. Epub 2012 Nov 10.

Smoker-nonsmoker differences in neural response to smoking-related and affective cues: an fMRI investigation.

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1
Department of Psychology and the Integrative Neuroscience Laboratory, Southern Illinois University, Carbondale, IL, USA. gusdiggs@siu.edu

Abstract

Smoking may sensitize brain systems to smoking cues while desensitizing systems to naturalistic rewards. This study examined smoker-nonsmoker differences in functional magnetic resonance imaging (fMRI) blood oxygen level dependent (BOLD) response to smoking-related and emotional images. Smokers, relative to nonsmokers, exhibited greater reactivity to smoking and decreased reactivity to emotional cues in the left middle frontal gyrus.

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