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PLoS One. 2012;7(11):e49170. doi: 10.1371/journal.pone.0049170. Epub 2012 Nov 7.

Molecular dissection of the basal clades in the human Y chromosome phylogenetic tree.

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1
Dipartimento di Biologia e Biotecnologie "Charles Darwin", Sapienza Università di Roma, Rome, Italy.

Abstract

One hundred and forty-six previously detected mutations were more precisely positioned in the human Y chromosome phylogeny by the analysis of 51 representative Y chromosome haplogroups and the use of 59 mutations from literature. Twenty-two new mutations were also described and incorporated in the revised phylogeny. This analysis made it possible to identify new haplogroups and to resolve a deep trifurcation within haplogroup B2. Our data provide a highly resolved branching in the African-specific portion of the Y tree and support the hypothesis of an origin in the north-western quadrant of the African continent for the human MSY diversity.

PMID:
23145109
PMCID:
PMC3492319
DOI:
10.1371/journal.pone.0049170
[Indexed for MEDLINE]
Free PMC Article
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