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Leukemia. 1990 Mar;4(3):235-7.

AcSDKP, an inhibitor of CFU-S proliferation, is synthesized in mice under steady-state conditions and secreted by bone marrow in long-term culture.

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1
INSERM U.250, Gustave-Roussy Institute, Villejuif, France.

Abstract

The peptide AcSDKP, isolated from fetal calf bone marrow, is able to prevent DNA synthesis in mouse CFU-S in vivo and in vitro. The molecule is demonstrated here to be constitutively produced in mice and synthesized by bone marrow cells in long term culture.

PMID:
2314120
[Indexed for MEDLINE]
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