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Cell Metab. 2012 Nov 7;16(5):559-64. doi: 10.1016/j.cmet.2012.10.007.

Gut microbiota composition and activity in relation to host metabolic phenotype and disease risk.

Author information

1
Biomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, UK.

Abstract

The symbiotic gut microbiota modulate health and disease of the host through a series of transgenomic metabolic and immune regulatory axes. We explore connections between microbiome composition and function related to individual metabolic phenotypes and consider these interactions as possible targets for developing new personalized therapies and clinical management strategies.

PMID:
23140640
DOI:
10.1016/j.cmet.2012.10.007
[Indexed for MEDLINE]
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