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Case Rep Oncol. 2012 Sep;5(3):537-41. doi: 10.1159/000343676. Epub 2012 Oct 5.

Primary small cell carcinoma of the tonsil: a case report and review of the literature.

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Hematology and Medical Oncology, University of Chicago, Chicago, Ill., USA.


Small cell cancer (SCC) of the tonsil is a rare and aggressive cancer. There are only 10 cases of tonsillar SCC reported in the English literature. We present a case of tonsillar SCC successfully treated with induction chemotherapy using carboplatin and etoposide followed by concurrent chemoradiation therapy with cisplatin as radiosensitizer. The patient remained free of recurrence after 3 years of follow-up. We also provide a succinct review of all tonsillar SCC cases reported in the English literature and their outcomes.


Carboplatin; Etoposide; Neuroendocrine tumor; Small cell cancer; Tonsillar cancer

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