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Virulence. 2013 Jan 1;4(1):82-4. doi: 10.4161/viru.22466. Epub 2012 Nov 7.

Diagnosis of influenza from lower respiratory tract sampling after negative upper respiratory tract sampling.

Author information

1
Divisions of Internal Medicine and Infectious Diseases, Toronto General Hospital, Toronto, ON, Canada. Isaac.Bogoch@uhn.ca

Abstract

In this retrospective cohort study, we demonstrate that PCR-confirmed diagnoses of influenza were made solely by lower respiratory sampling in 6.9% of cases, as traditional upper respiratory tract tests were negative, indeterminate or not performed. Clinical features of these cases are presented. Clinicians should consider lower respiratory tract sampling in select cases of influenza-like illness for diagnosis.

PMID:
23135351
PMCID:
PMC3544752
DOI:
10.4161/viru.22466
[Indexed for MEDLINE]
Free PMC Article

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