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J Neurointerv Surg. 2013 Nov;5(6):562-5. doi: 10.1136/neurintsurg-2012-010460. Epub 2012 Nov 6.

Onyx embolization for the endovascular treatment of infectious and traumatic aneurysms involving the cranial and cerebral vasculature.

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1
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Abstract

BACKGROUND:

Onyx is a liquid non-adhesive viscous embolic agent ideal for slow targeted injections which is currently approved for the treatment of intracranial aneurysms and arteriovenous malformations.

METHODS:

We performed a single-center retrospective analysis of consecutive patients who underwent off-label use of Onyx as the single embolic agent for the treatment of traumatic or infectious pseudoaneurysms involving the cerebral or cranial vasculature.

RESULTS:

A total of nine pseudoaneurysms treated by Onyx embolization were identified. Six of the pseudoaneurysms were post-surgical, one of the pseudoaneurysms was traumatic and two were infectious in nature. The mean pseudoaneurysm size was 5.9 mm (range 2-10 mm). Onyx-34 was used in all cases. Following treatment there was complete exclusion of all pseudoaneurysms including their inflow and outflow zones.

CONCLUSIONS:

Our experience demonstrates the efficacy and applicability of the use of Onyx in the treatment of complex traumatic and mycotic pseudoaneurysms involving the cerebral and cranial vascular tree.

KEYWORDS:

Aneurysm; Hemorrhage; Infection; Liquid Embolic Material; Technique

PMID:
23132531
DOI:
10.1136/neurintsurg-2012-010460
[Indexed for MEDLINE]
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