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Br J Neurosurg. 2013 Jun;27(3):388-9. doi: 10.3109/02688697.2012.739219. Epub 2012 Nov 7.

Glioblastoma multiforme intraxial metastasis to the conus medullaris with primary disease under control: a rare unexpected finding.

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  • 1Institute of Neurosurgery, Catholic University of Rome, Rome, Italy.


We report on glioblastoma multiple spinal intraaxial metastases with primary disease radiologically under control. The case highlights glioblastoma biological behavior and spread mechanisms; dissemination may have occurred initially and been controlled by chemotherapy, or more likely, is an indicator that even if radiologically dormant, disease is unlikely biologically inactive.

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