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Vaccine. 2012 Dec 17;31(1):149-53. doi: 10.1016/j.vaccine.2012.10.079. Epub 2012 Nov 3.

Using data to guide policy: next steps for preventing perinatal hepatitis B virus transmission in Cambodia.

Author information

1
Ministry of Health, Phnom Penh, Cambodia.

Abstract

BACKGROUND:

Cambodia is highly endemic for hepatitis B virus (HBV) infection. Preventing perinatal HBV transmission should be prioritized in health facilities by providing hepatitis B vaccination to all infants within 24 h of birth (timely birth dose coverage).

METHODS:

Teams assessed birth dose policy, practices and coverage in hospitals and health facilities in 10 provinces in Cambodia.

RESULTS:

Fifty-one sites were assessed. Median (interquartile range) timely birth dose coverage was 66% (48-92%); coverage was 88% (range=60-96%) in facilities vaccinating on-site and 48% (range=20-52%) in those referring off-site (p<0.0001). Overall, 5 (29%) of 16 hospitals that referred vaccination off-site did not tell mothers vaccination should take place within 24 h of birth, and 6 (35%) discharged mothers when no vaccination services were available for infants to receive the birth dose.

CONCLUSIONS:

Newborns can miss a time-sensitive opportunity to be protected against perinatal HBV infection when they are referred for vaccination off-site rather than being vaccinated in the delivery facility. These data support the case to strengthen policies and practices to provide hepatitis B birth dose vaccination in the delivery facility.

PMID:
23127515
PMCID:
PMC4663666
DOI:
10.1016/j.vaccine.2012.10.079
[Indexed for MEDLINE]
Free PMC Article
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