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Peptides. 2013 Jan;39:47-54. doi: 10.1016/j.peptides.2012.10.007. Epub 2012 Nov 2.

Biological applications of peptides nanotubes: an overview.

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Exact and Earth Sciences Department, Universidade Federal de São Paulo, UNIFESP, Diadema, SP, Brazil.


Recently, self-assemblies of peptide nanotubes (PNTs) have appeared as one of the most interesting nanostructures to be explored in the field of nanotechnology. These smart assemblies can have diverse applications, such as in the design of nanoreactors, sensors, electronics, and stimulus-responsive materials. Recent publications indicate that PNT synthesis and production are under extensive study. However, a more detailed safety and nanotoxicology evaluation of these materials is still necessary. This is of paramount importance since interesting and novel biomedical applications based on the use of PNTs, including the development of smart nanodevices and drug delivery systems, are under way. To this end, the aim of this mini-review is to discuss the recent biomedical applications of PNTs and, it hopes, to be a source of inspiration for researchers in different areas of expertise related to nanotechnology.

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