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Iran J Public Health. 2010;39(1):22-7. Epub 2010 Mar 31.

Prevalence of GBV-C RNA in HIV infected individuals in Tehran, Iran.

Author information

1
Dept. of Virology, School of Medicine, Iran University of Medical sciences, Iran.

Abstract

BACKGROUND:

GB virus C (GBV-C) is a flavivirus that was characterized in 1995. The prevalence of GBV-C RNA in HIV-infected subjects has not been previously studied in Iran and was therefore determined.

METHODS:

We have investigated serum samples of 80 patients from Imam Khomeini Hospital, Tehran, Iran, whose HIV infection was confirmed in our laboratory by Western-blotting. We used nested-PCR to detect GBV-C/HGV RNA in their sera.

RESULTS:

GBV-C/HGV RNA was detected in 15 (18.8%) of 80 patients. There was no significant difference in GBV-C/HGV RNA prevalence between males and females, in different age groups and HIV viral loads groups.

CONCLUSION:

The prevalence of GBV-C RNA was high in HIV-infected patients. There was no association between GBV-C RNA prevalence and specific gender, age, and HIV viral loads groups.

KEYWORDS:

Co-infection; GBV-C RNA; HIV; Iran

PMID:
23112986
PMCID:
PMC3468976
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