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Indian J Pharmacol. 2012 Sep-Oct;44(5):649-50. doi: 10.4103/0253-7613.100406.

Olanzapine induced de-novo obsessive compulsive disorder in a patient with schizophrenia.

Author information

1
Department of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India.

Abstract

There are reports of de novo development or exacerbation of obsessive-compulsive symptoms in patients with schizophrenia treated with atypical antipsychotics, although this is widely debated. We report one such case where a patient with a primary diagnosis of schizophrenia, treated with olanzapine, developed de novo obsessive-compulsive disorder, with convincing evidence for its causality due to the drug.

KEYWORDS:

Obsessive-compulsive disorder; olanzapine; schizophrenia

PMID:
23112432
PMCID:
PMC3480803
DOI:
10.4103/0253-7613.100406
[Indexed for MEDLINE]
Free PMC Article
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