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Mol Biol Cell. 2012 Nov;23(21):4167-70. doi: 10.1091/mbc.E12-05-0354.

Bringing the physical sciences into your cell biology research.

Author information

1
Department of Cell Biology and Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. dnr@jhmi.edu

Abstract

Historically, much of biology was studied by physicists and mathematicians. With the advent of modern molecular biology, a wave of researchers became trained in a new scientific discipline filled with the language of genes, mutants, and the central dogma. These new molecular approaches have provided volumes of information on biomolecules and molecular pathways from the cellular to the organismal level. The challenge now is to determine how this seemingly endless list of components works together to promote the healthy function of complex living systems. This effort requires an interdisciplinary approach by investigators from both the biological and the physical sciences.

PMID:
23112230
PMCID:
PMC3484095
DOI:
10.1091/mbc.E12-05-0354
[Indexed for MEDLINE]
Free PMC Article

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