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Curr Genet. 1990 Jan;17(1):77-9.

Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast.

Author information

1
Institut für Mikrobiologie, Technische Hochschule Darmstadt, Federal Republic of Germany.

Abstract

suc2 degrees is a naturally occurring amber mutant allele of the yeast invertase structural gene SUC2. Strains carrying suc2 degrees had only 10% of the wild type invertase-specific mRNA level. Amber suppressors, which allowed suc2 degree strains to ferment sucrose caused an increase of the SUC-specific mRNA level.

PMID:
2311129
DOI:
10.1007/bf00313252
[Indexed for MEDLINE]

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