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Acta Physiol (Oxf). 2013 Jan;207(1):34-9. doi: 10.1111/apha.12011. Epub 2012 Oct 30.

From urothelial signalling to experiencing a sensation related to the urinary bladder.

Author information

1
Departments of Medicine and Pharmacology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. lbirder@pitt.edu

Abstract

The mechanisms underlying bladder sensation and the way we experience sensations during normal voiding and in pathology is complex and not well understood. During storage and emptying, mechanical changes occurring in number of cell types within the bladder wall (i.e. the uroepithelium and bladder afferents) can have a major influence on our sensory systems. In this review, we discuss bladder sensation with a focus on coding events in the periphery.

PMID:
23110490
PMCID:
PMC4034264
DOI:
10.1111/apha.12011
[Indexed for MEDLINE]
Free PMC Article

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