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Korean J Pathol. 2012 Feb;46(1):96-100. doi: 10.4132/KoreanJPathol.2012.46.1.96. Epub 2012 Feb 23.

Adenocarcinoma with intraductal papillary mucinous neoplasm arising in jejunal heterotopic pancreas.

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Department of Pathology, Inha University School of Medicine, Incheon, Korea.


A 74-year-old man suffered from jejunal perforation and adhesion to sigmoid colon due to adenocarcinoma associated with intraductal papillary mucinous neoplasm (IPMN) arising in a jejunal heterotopic pancreas. The jejunal lesion showed direct extension to the sigmoid colon, which was mistaken as sigmoid colon cancer by surgeons. Malignant transformation is a rare complication of a heterotopic pancreas. About half of malignancies in reported cases were ductal adenocarcinoma arising in the stomach, and the jejunal location is extremely rare. Furthermore, IPMN is also uncommon finding in a heterotopic pancreas.


Adenocarcinoma; Heterotopia; Jejunum; Pancreas

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