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Int J STD AIDS. 2012 Oct;23(10):756-7. doi: 10.1258/ijsa.2012.012124.

Optimal treatment for asymptomatic neurosyphilis.

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1
Section of Infectious Diseases, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan and National Yang-Ming University, 386 Ta-Chung 1st Road, Kaohsiung 813, Taipei, Taiwan, ROC.

Abstract

In the pre-penicillin era, patients with asymptomatic neurosyphilis (ANS) were more likely to develop long-term neurological sequelae than those patients with normal cerebrospinal fluid (CSF). Although benzathine penicillin G cannot achieve treponemicidal levels in the CSF, decreased rates of neurological complications of syphilis and non-treponemal titre serological responses are usually observed after treatment with this antibiotic. We here a homosexual man with ANS successfully treated with benzathine penicillin G. This case suggests that reconsideration on the necessity of a lumbar puncture in HIV-infected patients with ANS is warranted.

PMID:
23104753
DOI:
10.1258/ijsa.2012.012124
[Indexed for MEDLINE]
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