Send to

Choose Destination
See comment in PubMed Commons below
Int J Syst Evol Microbiol. 2013 Jun;63(Pt 6):2146-54. doi: 10.1099/ijs.0.046979-0. Epub 2012 Oct 26.

Emendation of the description of the species Corynebacterium propinquum to include strains which produce urease.

Author information

Special Bacteriology Unit, ARNI, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.


Corynebacterium propinquum is a Gram-positive rod occasionally recovered from clinical infections which, according to 16S rRNA gene sequencing, is most closely related (>99% sequence similarity) to Corynebacterium pseudodiphtheriticum. The two species are very similar biochemically, commonly differentiated by a single test, the detection of urease, where strains of C. propinquum are described as being urease-non-producing and strains of C. pseudodiphtheriticum are described as urease-producing. In this study, historical and contemporary strains of C. propinquum and C. pseudodiphtheriticum from this laboratory were definitively characterized, which included use of rpoB sequencing. Urease-producing strains of C. propinquum as well as typical urease-non-producing isolates were identified after rpoB sequencing, with six of these being originally identified as C. pseudodiphtheriticum. Based on these observations, we propose emendation of the description of C. propinquum to include strains which produce urease. MALDI-TOF analysis may be a useful tool to differentiate these taxa. Existing commercial databases should be updated to include urease-positive strains of C. propinquum.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons


    Supplemental Content

    Full text links

    Icon for Ingenta plc
    Loading ...
    Support Center