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Nat Genet. 2012 Nov;44(11):1176-7. doi: 10.1038/ng.2449.

FOXA1 and breast cancer risk.

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1
Cancer Research UK, Cambridge, UK.

Abstract

Many SNPs associated with human disease are located in non-coding regions of the genome. A new study shows that SNPs associated with breast cancer risk are located in enhancer regions and alter binding affinity for the pioneer factor FOXA1.

PMID:
23104063
DOI:
10.1038/ng.2449
[Indexed for MEDLINE]
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