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Insulin Delivery and Glucose Monitoring Methods for Diabetes Mellitus: Comparative Effectiveness.

Authors

John M. Eisenberg Center for Clinical Decisions and Communications Science.

Source

Comparative Effectiveness Review Summary Guides for Clinicians [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2007-.
AHRQ Comparative Effectiveness Reviews.
2012 Sep 04.

Excerpt

In response to a public request regarding the benefits and harms of current modes of intensive insulin therapy (continuous subcutaneous insulin infusion [CSII] vs. multiple daily injections [MDI]) and modes of blood glucose monitoring (real-time continuous glucose monitoring [rt-CGM] vs. self-monitoring of blood glucose [SMBG]), the Agency for Healthcare Research and Quality (AHRQ) contracted with the Evidence-based Practice Center at Johns Hopkins University to conduct a systematic review of these modalities. Forty-one studies in 44 publications met the inclusion criteria. Outcomes including glycemic control, hypoglycemia, quality of life, and clinical outcomes were assessed in individuals with type 1 diabetes, type 2 diabetes, or pre-existing diabetes in pregnancy. The review did not include pregnant women with gestational diabetes and patients with maturity-onset diabetes of the young in its evaluation. The full report, listing all studies, is available at www.effectivehealthcare.ahrq.gov/glucose.cfm. This summary, based on the full report of research evidence, is provided to assist in decisionmaking along with consideration of a patient’s values and preferences. However, reviews of evidence should not be construed to represent clinical recommendations or guidelines.

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