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The recently identified hexosaminidase D enzyme substantially contributes to the elevated hexosaminidase activity in rheumatoid arthritis.
Immunol Lett. 2013 Jan;149(1-2):71-6. doi: 10.1016/j.imlet.2012.10.012. Epub 2012 Oct 23.
Immunol Lett. 2013.
PMID: 23099419
Clinical Trial.
Mechanism of Human Nucleocytoplasmic Hexosaminidase D.
Alteen MG, Oehler V, Nemčovičová I, Wilson IB, Vocadlo DJ, Gloster TM.
Alteen MG, et al.
Biochemistry. 2016 May 17;55(19):2735-47. doi: 10.1021/acs.biochem.5b01285. Epub 2016 May 5.
Biochemistry. 2016.
PMID: 27149221
Free PMC article.
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