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Chromosoma. 2012 Dec;121(6):527-38. doi: 10.1007/s00412-012-0386-5. Epub 2012 Oct 26.

CENP-A: the key player behind centromere identity, propagation, and kinetochore assembly.

Author information

1
Institute for Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal, C.P. 6128, Succursale Centre-ville, Montréal, Québec H3C 3J7, Canada. valerie.de.rop@umontreal.ca

Abstract

Chromosome segregation is the one of the great problems in biology with complexities spanning from biophysics and polymer dynamics to epigenetics. Here, we summarize the current knowledge and highlight gaps in understanding of the mechanisms controlling epigenetic regulation of chromosome segregation.

PMID:
23095988
PMCID:
PMC3501172
DOI:
10.1007/s00412-012-0386-5
[Indexed for MEDLINE]
Free PMC Article

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