Format

Send to

Choose Destination
See comment in PubMed Commons below
Cornea. 2013 Jun;32(6):816-20. doi: 10.1097/ICO.0b013e31826a1e53.

Surgical resection and amniotic membrane transplantation for treatment of refractory giant papillae in vernal keratoconjunctivitis.

Author information

  • 1Department of Ophthalmology, Shenzhen Eye Hospital, Jinan University, Shenzhen, China.

Abstract

PURPOSE:

The aim of this study was to evaluate the outcome of surgical resection and amniotic membrane transplantation (AMT) for treatment of refractory symptomatic giant papillae in vernal keratoconjunctivitis (VKC).

METHODS:

This is a retrospective study of 13 eyes of 9 patients with refractory giant papillae associated with corneal shield ulcer and/or punctate epithelial erosions who underwent surgical resection of the papillae combined with AMT to cover the tarsal conjunctival defect.

RESULTS:

During 14.2 ± 4.2 months of postoperative follow-up, smooth tarsal conjunctival surface was achieved in all cases, with no recurrence of the giant papillae in any eye. Corneal shield ulcers and punctate epithelial erosions healed within 2 weeks after surgery and did not recur during the follow-up. Best-corrected visual acuity improved from 0.26 ± 0.21 logarithm of the minimum angle of resolution preoperatively to 0.02 ± 0.04 logarithm of the minimum angle of resolution postoperatively (P = 0.01). Three patients experienced recurrence of VKC symptoms, but without giant papillae, which could be well controlled by topical medications.

CONCLUSIONS:

Surgical resection combined with AMT is an effective procedure for treatment of refractory giant papillae in patients with VKC.

PMID:
23086371
DOI:
10.1097/ICO.0b013e31826a1e53
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Lippincott Williams & Wilkins
    Loading ...
    Support Center