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Immunity. 2012 Oct 19;37(4):598-600. doi: 10.1016/j.immuni.2012.10.005.

Maintaining a competitive edge: new rules for peripheral T cell homeostasis.

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1
Medical Research Council Centre for Immune Regulation, University of Birmingham Medical School, UK. l.s.walker@bham.ac.uk

Abstract

The contraction of T cell populations after immune responses is poorly understood. In this issue of Immunity, Singh et al. show that "deletor" T cells regulate the frequency of antigen-specific T cells by competing for shared subthreshold ligands.

PMID:
23084356
DOI:
10.1016/j.immuni.2012.10.005
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