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Int J Artif Organs. 2012 Oct;35(10):847-53. doi: 10.5301/ijao.5000164.

In vitro antibacterial activity of different self-etch adhesives.

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Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, School of Dentistry, University of Pavia, Pavia, Italy.



The aim of this study was to evaluate and compare the antimicrobial activity of different self-etch adhesives by means of the agar disc diffusion test.


Streptococcus salivarius, Streptococcus sanguis and Streptococcus mutans strains were selected to evaluate the antimicrobial activity of various self-etch adhesives (Futurabond NR, G-aenial Bond, Adper™ Easy Bond Self-Etch Adhesive, Clearfil Protect Bond, One Coat 7.0, Clearfil S3 Bond, Clearfil SE Bond) using the agar disc diffusion test; 0.2% Chlorexidine digluconate was used as control. Paper disks were saturated with 10 µL of each adhesive system and placed onto culture agar plates pre-adsorbed with bacterial cells and further incubated for 24 h at 37°C. The growth inhibition zones around each adhesive were recorded and compared for each bacterial strain.


The test results of the various self-etch adhesives were significantly different.


The results of the present investigation showed that the addition of MDPB monomer to an adhesive system enhances its antibacterial effect against S. salivarius, S. sanguis and S. mutans.

[Indexed for MEDLINE]

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