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Genome Biol. 2012 Oct 18;13(10):172. doi: 10.1186/gb-2012-13-10-172.

DNA methylation studies using twins: what are they telling us?

Abstract

Recent studies have identified both heritable DNA methylation effects and differential methylation in disease-discordant identical twins. Larger sample sizes, replication, genetic-epigenetic analyses and longitudinal assays are now needed to establish the role of epigenetic variants in disease.

PMID:
23078798
PMCID:
PMC3491399
DOI:
10.1186/gb-2012-13-10-172
[Indexed for MEDLINE]
Free PMC Article

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