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Cornea. 2013 Apr;32(4):e25-30. doi: 10.1097/ICO.0b013e318261eb2b.

Optical coherence tomography and ultrasound biomicroscopy imaging of opaque corneas.

Author information

1
Corneal Division, Zhongshan Ophthalmic Center at Sun Yat-sen University, The State Key Laboratory of Ophthalmology, Guangzhou, China.

Abstract

PURPOSE:

The purpose was to determine the interchangeability of ultrasound biomicroscopy (UBM) and anterior segment optical coherence tomography (AS-OCT) for corneal opacity depth measurement.

METHODS:

Twenty-six eyes of 26 consecutive patients with corneal opacities were examined by both AS-OCT and UBM. The corneal thickness and the corneal opacity depth were measured and compared. The interchangeability was determined by Bland-Altman plotting.

RESULTS:

The difference in the full corneal thickness and in the corneal opacity depth between OCT and UBM was 5 ± 7 μm and -1 ± 8 μm, respectively. There were strong correlations and no significant differences between the paired parameters (all r > 0.99, P < 0.01). The limits of agreement were 5 ± 14 μm for the corneal thickness and -1 ± 14.8 μm for the corneal opacity depth.

CONCLUSIONS:

AS-OCT and UBM may be used interchangeably for measuring both full corneal thickness and corneal opacity depth in patients with corneal opacity.

PMID:
23073488
PMCID:
PMC3993526
DOI:
10.1097/ICO.0b013e318261eb2b
[Indexed for MEDLINE]
Free PMC Article

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