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Bioinformatics. 2012 Dec 15;28(24):3318-9. doi: 10.1093/bioinformatics/bts607. Epub 2012 Oct 15.

MULTOVL: fast multiple overlaps of genomic regions.

Author information

1
Scientific Computing Core Facility, Campus Science Support Facilities, 1030 Vienna, Austria. andras.aszodi@csf.ac.at

Abstract

We present the MULTOVL application suite that detects and statistically analyses multiple overlaps of genomic regions in a fast and efficient manner. The package supports the detection of multiple region intersections, unions and 'solitary' genomic regions. The significance of actually observed overlaps is estimated by comparing them with empirical null distributions generated by random shuffling of the input regions.

PMID:
23071271
DOI:
10.1093/bioinformatics/bts607
[Indexed for MEDLINE]

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