Format

Send to

Choose Destination
See comment in PubMed Commons below
Klin Padiatr. 2012 Nov;224(7):448-52. doi: 10.1055/s-0032-1323835. Epub 2012 Oct 15.

Reduced platelet aggregation in a boy with scurvy.

Author information

1
Department of Child Neurology, University of Giessen, Giessen, Germany. Friederike.Dey@paediat.med.uni-giessen.de

Abstract

Pediatric scurvy is a rare condition characterized by perifollicular petechiae and bruising, hemorrhagic gingivitis and musculoskeletal symptoms, all assumed to be predominantly related to abnormal collagen structure. We report on a 9-year-old autistic boy with vitamin C deficiency due to a highly limited food range presenting with multiple petechiae, gum bleeding and debilitating bone pain, in whom platelet aggregometry revealed a distinctly reduced thrombocyte aggregation, normalizing after vitamin C supplementation. This observation indicates that platelet dysfunction may additionally contribute to the hemorrhagic diathesis in scurvy, and demonstrates that ascorbic acid deficiency should be considered in children with an otherwise unexplained acquired thrombocytopathy.

PMID:
23070864
DOI:
10.1055/s-0032-1323835
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Georg Thieme Verlag Stuttgart, New York
    Loading ...
    Support Center