Format

Send to

Choose Destination
Cytometry. 1990;11(1):8-25.

A unified model of eukaryotic chromosomes.

Author information

1
Section of Neuropathology, Yale University Medical School, New Haven, Connecticut 06510.

Abstract

A revised model of DNA packaging into chromosomes is presented. Its features are consistent with observed structural dimensions and the molecular periodicities related to transcription, replication and matrix attachment domains. The transitions between euchromatic, heterochromatic and metaphase states are explained simply. Molecular and physical properties of chromosomal bands, and their correlation with specific DNA sequence motifs are discussed.

PMID:
2307065
DOI:
10.1002/cyto.990110104
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center