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Am J Obstet Gynecol. 2012 Dec;207(6):502.e1-8. doi: 10.1016/j.ajog.2012.09.019. Epub 2012 Sep 22.

Induction of labor compared to expectant management in low-risk women and associated perinatal outcomes.

Author information

1
Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Medicine, School of Medicine, University of California-San Francisco, CA, USA.

Abstract

OBJECTIVE:

We sought to examine the association of labor induction and perinatal outcomes.

STUDY DESIGN:

This was a retrospective cohort study of low-risk nulliparous women with term, live births. Women who had induction at a given gestational age (eg, 39 weeks) were compared to delivery at a later gestation (eg, 40, 41, or 42 weeks).

RESULTS:

Compared to delivery at a later gestational age, those induced at 39 weeks had a lower risk of cesarean (adjusted odds ratio [aOR], 0.90; 95% confidence interval [CI], 0.88-0.91) and labor dystocia (aOR, 0.88; 95% CI, 0.84-0.94). Their neonates had lowered risk of having 5-minute Apgar <7 (aOR, 0.81; 95% CI, 0.72-0.92), meconium aspiration syndrome (aOR, 0.30; 95% CI, 0.19-0.48), and admission to neonatal intensive care unit (aOR, 0.87; 95% CI, 0.78-0.97). Similar findings were seen for women who were induced at 40 weeks compared to delivery later.

CONCLUSION:

Induction of labor in low-risk women at term is not associated with increased risk of cesarean delivery compared to delivery later.

PMID:
23063017
PMCID:
PMC3719847
DOI:
10.1016/j.ajog.2012.09.019
[Indexed for MEDLINE]
Free PMC Article

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