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J Med Screen. 2012 Sep;19(3):123-6. doi: 10.1258/jms.2012.012024. Epub 2012 Oct 11.

Neonatal screening for congenital hypothyroidism in East Azerbaijan, Iran: the first report.

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1
Department of Community Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. zenalali@gmail.com

Abstract

OBJECTIVES:

To investigate the prevalence of congenital hypothyroidism (CH) among neonates in East Azerbaijan, Iran.

METHODS:

A cross-sectional study conducted from 2009 to 2010. Most heel blood samples were taken between three and seven days of birth. Thyroid stimulating hormone (TSH) was tested using the enzyme-linked immunosorbent assay method. Neonates with abnormal screening results (TSH>20 mIU/L, T4<6.5 mg/dL) were re-examined. Data were analysed using SPSS software.

RESULTS:

A total of 62,459 infants were screened. Of 1562 re-called subjects (re-call rate 2.5%), 94 cases with CH were detected, yielding a CH prevalence of 1:666 (female:male ratio 1:1.4).

CONCLUSION:

The prevalence of CH in East Azerbaijan province is higher in comparison with worldwide levels. These results emphasize the importance of the neonatal screening programme.

PMID:
23060475
DOI:
10.1258/jms.2012.012024
[Indexed for MEDLINE]
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