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Curr Gastroenterol Rep. 2012 Dec;14(6):489-96. doi: 10.1007/s11894-012-0296-y.

Helicobacter pylori in gastric malignancies.

Author information

1
Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0063, USA. abbhandari2@ad.ucsd.edu

Abstract

Helicobacter pylori infection remains common worldwide and is significantly associated with gastric adenocarcinoma and gastric mucosa-associated lymphoid tissue (MALT)lymphoma. This article reviews recent developments in the field of H. pylori with an emphasis on mechanisms of carcinogenesis, and the bacterial, environmental and host factors that may alter risk of developing gastric cancer or gastric MALT lymphoma. The topic of eradication of H. pylori to prevent the development of malignancy and the possibility of a vaccine against H. pylori are also explored.

PMID:
23054813
DOI:
10.1007/s11894-012-0296-y
[Indexed for MEDLINE]

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