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Ann N Y Acad Sci. 2012 Oct;1271:97-103. doi: 10.1111/j.1749-6632.2012.06726.x.

Diversification and conservation of the extraembryonic tissues in mediating nutrient uptake during amniote development.

Author information

1
Lab for Early Embryogenesis, RIKEN Center for Developmental Biology, Kobe, Hyogo, Japan. sheng@cdb.riken.jp

Abstract

The transfer of nutrients from the mother through the chorioallantoic placenta meets the nutritional needs of the embryo during human prenatal development. Although all amniotes start with a similar "tool kit" of extraembryonic tissues, an enormous diversity of extraembryonic tissue formation has evolved to accommodate embryological and physiological constraints unique to their developmental programs. A comparative knowledge of these extraembryonic tissues and their role in nutrient uptake during development is required to fully appreciate the adaptive changes in placental mammals. Here, we offer a comparative embryological perspective and propose that there are three conserved nutrient transfer routes among the amniotes. We highlight the importance of the yolk sac endoderm, thought to be a vestigial remnant of our amniote lineage, in mediating nutrient uptake during early human development. We also draw attention to the similarity between yolk sac endoderm-mediated and trophectoderm-mediated nutrient uptake.

PMID:
23050970
PMCID:
PMC3499656
DOI:
10.1111/j.1749-6632.2012.06726.x
[Indexed for MEDLINE]
Free PMC Article

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