Abstract
A series of sterically shielded pyrrolidine nitroxides were synthesized, and their reduction by ascorbate (vitamin C) indicate that nitroxide 3, a tetraethyl derivative of 3-carboxy-PROXYL, is reduced at the slowest rate among known nitroxides, i.e., at a 60-fold slower rate than that for 3-carboxy-PROXYL.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Ascorbic Acid / chemistry
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Kinetics
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Models, Molecular
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Molecular Structure
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Nitrogen Oxides / chemical synthesis*
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Oxidation-Reduction
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Pyrrolidines / chemical synthesis*
Substances
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Nitrogen Oxides
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Pyrrolidines
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nitroxyl
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pyrrolidine
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Ascorbic Acid