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BMJ Case Rep. 2012 Oct 9;2012. pii: bcr2012007044. doi: 10.1136/bcr-2012-007044.

Tianeptine in combination with monoamine oxidase inhibitors for major depressive disorder.

Author information

1
Department of Psychiatry, Cooper Medical School of Rowan University, NJ, USA. edward.tobe@comcast.net

Abstract

Major depressive disorder may respond to monotherapy with monoamine oxidase inhibitors (MAOIs) or tianeptine. Literature search showed no reports of MAOIs combined with tianeptine. The method included was clinical case history. A 59-year-old woman had partial improvement of depression with the MAOI tranylcypromine combined with topiramate, trazodone and ziprasidone. The patient had further improvement of depression symptoms after addition of tianeptine. No adverse events were evident. The combination of MAIOs and tianeptine may be effective for refractory major depressive disorder.

PMID:
23048001
PMCID:
PMC4312778
DOI:
10.1136/bcr-2012-007044
[Indexed for MEDLINE]
Free PMC Article

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