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Int J Epidemiol. 2012 Oct;41(5):1480-9. doi: 10.1093/ije/dys147.

Case-control studies: basic concepts.

Author information

1
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands. J.P.Vandenbroucke@lumc.nl

Abstract

The purpose of this article is to present in elementary mathematical and statistical terms a simple way to quickly and effectively teach and understand case-control studies, as they are commonly done in dynamic populations-without using the rare disease assumption. Our focus is on case-control studies of disease incidence ('incident case-control studies'); we will not consider the situation of case-control studies of prevalent disease, which are published much less frequently.

PMID:
23045208
DOI:
10.1093/ije/dys147
[Indexed for MEDLINE]
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